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Optics Letters

Optics Letters


  • Vol. 29, Iss. 19 — Oct. 1, 2004
  • pp: 2252–2254

Polarization-resolved second-harmonic-generation optical coherence tomography in collagen

Brian E. Applegate, Changhuei Yang, Andrew M. Rollins, and Joseph A. Izatt  »View Author Affiliations

Optics Letters, Vol. 29, Issue 19, pp. 2252-2254 (2004)

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We describe a novel imaging technique, second-harmonic-generation optical coherence tomography (SHOCT). This technique combines the spatial resolution and depth penetration of optical coherence tomography (OCT) with the molecular sensitivity of second-harmonic-generation spectroscopy. As a consequence of the coherent detection required for OCT, polarization-resolved images arise naturally. We demonstrate this new technique on a skin sample from the belly of Icelandic salmon, acquiring polarization-resolved SHOCT and OCT images simultaneously.

© 2004 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(190.4160) Nonlinear optics : Multiharmonic generation
(190.4710) Nonlinear optics : Optical nonlinearities in organic materials

Brian E. Applegate, Changhuei Yang, Andrew M. Rollins, and Joseph A. Izatt, "Polarization-resolved second-harmonic-generation optical coherence tomography in collagen," Opt. Lett. 29, 2252-2254 (2004)

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