The possibility of measuring a full Doppler flow depth profile in parallel by use of frequency-domain optical coherence tomography is demonstrated. The method is based on a local phase analysis of the backscattered signal and allows for imaging of bidirectional Doppler flow. The Doppler frequency limit is 5 kHz for the presented measurements and is set by half of the frame rate of the CCD detector array. We measured the flow of 0.3-μm microspheres suspended in distilled water at controlled flow rates and <i>in vitro</i> human blood flow through a 200-μm capillary with a real-time color-encoded Doppler tomogram rate of 2–3/s.
© 2004 Optical Society of America
(170.3340) Medical optics and biotechnology : Laser Doppler velocimetry
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.4500) Medical optics and biotechnology : Optical coherence tomography
Rainer A. Leitgeb, Leopold Schmetterer, Christoph K. Hitzenberger, Adolf F. Fercher, Fatma Berisha, Maciej Wojtkowski, and Tomasz Bajraszewski, "Real-time measurement of in vitro flow by Fourier-domain color Doppler optical coherence tomography," Opt. Lett. 29, 171-173 (2004)