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Optics Letters

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  • Vol. 29, Iss. 20 — Oct. 15, 2004
  • pp: 2405–2407

Time-resolved spectrophotometer for turbid media based on supercontinuum generation in a photonic crystal fiber

Andrea Bassi, Johannes Swartling, Cosimo D'Andrea, Antonio Pifferi, Alessandro Torricelli, and Rinaldo Cubeddu  »View Author Affiliations


Optics Letters, Vol. 29, Issue 20, pp. 2405-2407 (2004)
http://dx.doi.org/10.1364/OL.29.002405


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Abstract

We describe an instrument for the time-resolved spectroscopy of turbid media that is based on supercontinuum generation in a photonic crystal fiber. The light injected into the sample consists of subpicosecond pulses that cover 550–1000 nm at 85 MHz at an average power of as much as 40 mW. A spectrometer coupled to a multianode photomultiplier tube is used to detect the light simultaneously in 16 wavelength channels, with a resolution of 5–20 nm/channel, depending on the grating. Time-correlated single-photon counting is used to produce time-dispersion curves, which one fits to the diffusion equation to determine absorption and reduced scattering coefficients. We tested the instrument by measuring the time-resolved diffuse reflectance of epoxy phantoms and by performing <i>in vivo</i> measurements on volunteers. The results were similar to those obtained with previous discrete wavelength systems, whereas the full spectrum (610–810 nm) acquisition time was as short as 1 s owing to the parallel acquisition.

© 2004 Optical Society of America

OCIS Codes
(120.6200) Instrumentation, measurement, and metrology : Spectrometers and spectroscopic instrumentation
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics
(170.7050) Medical optics and biotechnology : Turbid media
(300.6500) Spectroscopy : Spectroscopy, time-resolved

Citation
Andrea Bassi, Johannes Swartling, Cosimo D'Andrea, Antonio Pifferi, Alessandro Torricelli, and Rinaldo Cubeddu, "Time-resolved spectrophotometer for turbid media based on supercontinuum generation in a photonic crystal fiber," Opt. Lett. 29, 2405-2407 (2004)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-29-20-2405


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References

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