OSA's Digital Library

Optics Letters

Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Vol. 29, Iss. 23 — Dec. 1, 2004
  • pp: 2701–2703

Simple approach to one-laser, broadband coherent anti-Stokes Raman scattering microscopy

Tak W. Kee and Marcus T. Cicerone  »View Author Affiliations


Optics Letters, Vol. 29, Issue 23, pp. 2701-2703 (2004)
http://dx.doi.org/10.1364/OL.29.002701


View Full Text Article

Acrobat PDF (454 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

Coherent anti-Stokes Raman scattering (CARS) microscopy is emerging as a powerful method for imaging materials and biological systems, partly because of its noninvasiveness and selective chemical sensitivity. However, its full potential for species-selective imaging is limited by a restricted spectral bandwidth. Recent increases in bandwidth are promising but still are not sufficient for the level of robust component discrimination that would be needed in a chemically complex milieu found, for example, in intracellular and extracellular environments. We demonstrate a truly broadband CARS imaging instrument that we use to acquire hyperspectral images with vibrational spectra over a bandwidth of 2500 cm-1 with a resolution of 13 cm-1.

OCIS Codes
(110.4190) Imaging systems : Multiple imaging
(180.6900) Microscopy : Three-dimensional microscopy
(190.4380) Nonlinear optics : Nonlinear optics, four-wave mixing
(300.6230) Spectroscopy : Spectroscopy, coherent anti-Stokes Raman scattering

Citation
Tak W. Kee and Marcus T. Cicerone, "Simple approach to one-laser, broadband coherent anti-Stokes Raman scattering microscopy," Opt. Lett. 29, 2701-2703 (2004)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-29-23-2701


Sort:  Author  |  Year  |  Journal  |  Reset

References

  1. M. D. Duncan, J. Reintjes, and T. J. Manuccia, Opt. Lett. 7, 350 (1982).
  2. A. Zumbusch, G. R. Holtom, and X. S. Xie, Phys. Rev. Lett. 82, 4142 (1999).
  3. J. X. Chen, A. Volkmer, L. D. Book, and X. S. Xie, J. Phys. Chem. B 106, 8493 (2002).
  4. M. Muller and J. M. Schins, J. Phys. Chem. B 106, 3715 (2002).
  5. T. C. B. Schut, R. Wolthuis, P. J. Caspers, and G. J. Puppels, J. Raman Spectrosc. 33, 580 (2002).
  6. K. Konig, P. T. C. So, W. W. Mantulin, and E. Gratton, Opt. Lett. 22, 135 (1997).
  7. Certain commercial equipment and materials are identified in this Letter to specify adequately the experimental procedure. In no case does such identification imply recommendation by the National Institute of Standards and Technology, nor does it imply that the material or equipment identified is necessarily the best available for this purpose.
  8. A. M. Weiner, J. P. Heritage, and E. M. Kirschner, J. Opt. Soc. Am. B 5, 1563 (1988).
  9. T. A. Birks, W. J. Wadsworth, and P. St. J. Russell, Opt. Lett. 25, 1415 (2000).
  10. D. J. Jones, E. O. Potma, J. X. Cheng, B. Burfeindt, Y. Pang, J. Ye, and X. S. Xie, Rev. Sci. Instrum. 73, 2843 (2002).
  11. H. N. Paulsen, K. M. Hilligsoe, J. Thogersen, S. R. Keiding, and J. J. Larsen, Opt. Lett. 28, 1123 (2003).
  12. D. Oron, N. Dudovich, D. Yelin, and Y. Silberberg, Phys. Rev. Lett. 88, 063004 (2002).
  13. R. L. McCreery, http://www.chemistry.ohio-state.edu/~rmccreer/freqcorr/images/benzo.html.
  14. J. X. Cheng, Y. K. Jia, G. F. Zheng, and X. S. Xie, Biophys. J. 83, 502 (2002).

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited