An ultrahigh-speed spectral domain optical coherence tomography (SD-OCT) system is presented that achieves acquisition rates of 29,300 depth profiles/s. The sensitivity of SD-OCT and time domain OCT (TD-OCT) are experimentally compared, demonstrating a 21.7-dB improvement of SD-OCT over TD-OCT. <i>In vivo</i> images of the human retina are presented, demonstrating the ability to acquire high-quality structural images with an axial resolution of 6 µm at ultrahigh speed and with an ocular exposure level of less than 600 μW.
© 2004 Optical Society of America
(030.4280) Coherence and statistical optics : Noise in imaging systems
(110.4280) Imaging systems : Noise in imaging systems
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.4500) Medical optics and biotechnology : Optical coherence tomography
Nader Nassif, Barry Cense, B. Hyle Park, Seok H. Yun, Teresa C. Chen, Brett E. Bouma, Guillermo J. Tearney, and Johannes F. de Boer, "In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography," Opt. Lett. 29, 480-482 (2004)