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Optics Letters

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  • Vol. 30, Iss. 1 — Jan. 1, 2005
  • pp: 58–60

Simultaneous optical coherence tomography-Indocyanine Green dye fluorescence imaging system for investigations of the eye's fundus

George M. Dobre, Adrian Gh. Podoleanu, and Richard B. Rosen  »View Author Affiliations


Optics Letters, Vol. 30, Issue 1, pp. 58-60 (2005)
http://dx.doi.org/10.1364/OL.30.000058


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Abstract

We have developed a dual-channel optical coherence tomography-Indocyanine Green dye (OCT-ICG) fluorescence system based on a previously reported ophthalmic OCT confocal imaging system. The confocal channel is tuned to the fluorescence wavelength range of the ICG, and light from the same optical source is used to generate the OCT image and to excite the ICG fluorescence. The system enables the clinician to visualize simultaneously en face OCT slices and corresponding ICG angiograms of the ocular fundus, displayed side by side. C-scan (constant depth) and B-scan (cross section) images are collected by a fast en face scan (T scan). The pixel-to-pixel correspondence between the OCT and angiography images allows the user to capture OCT Bscans precisely at selected points on the ICG confocal images.

© 2005 Optical Society of America

OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.1790) Medical optics and biotechnology : Confocal microscopy
(170.2520) Medical optics and biotechnology : Fluorescence microscopy
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.6280) Medical optics and biotechnology : Spectroscopy, fluorescence and luminescence

Citation
George M. Dobre, Adrian Gh. Podoleanu, and Richard B. Rosen, "Simultaneous optical coherence tomography-Indocyanine Green dye fluorescence imaging system for investigations of the eye's fundus," Opt. Lett. 30, 58-60 (2005)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-30-1-58


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References

  1. A. Scheider and C. Schroedel, Am. J. Ophthalmol. 108, 458 (1989).
  2. L. A. Yanuzzi, R. W. Flower, and J. S. Slatker, eds., Indocyanine Green Angiography, (Mosby, St.Louis, Mo., 1997).
  3. W. J. Geeraets and E. R. Berry, Am. J. Opththalmol. 66, 15 (1968).
  4. A. Gh. Podoleanu, G. M. Dobre, and D. A. Jackson, Opt. Lett. 23, 147 (1998).
  5. A. Gh. Podoleanu, J. A. Rogers, and D. A. Jackson, Opt. Express 7, 292 (2000), http://www.opticsexpress.org.
  6. J. P. Villeneuve, R. Huot, D. Marleau, and P. M. Huet, Am. J. Gastroenterol. 77, 233 (1982).

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