OSA's Digital Library

Optics Letters

Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Vol. 30, Iss. 10 — May. 15, 2005
  • pp: 1165–1167

Hilbert phase microscopy for investigating fast dynamics in transparent systems

Takahiro Ikeda, Gabriel Popescu, Ramachandra R. Dasari, and Michael S. Feld  »View Author Affiliations


Optics Letters, Vol. 30, Issue 10, pp. 1165-1167 (2005)
http://dx.doi.org/10.1364/OL.30.001165


View Full Text Article

Acrobat PDF (340 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

We introduce Hilbert phase microscopy (HPM) as a novel optical technique for measuring high transverse resolution quantitative phase images associated with optically transparent objects. Because of its single-shot nature, HPM is suitable for investigating rapid phenomena that take place in transparent structures such as biological cells. The potential of this technique for studying biological systems is demonstrated with measurements of red blood cells, and its ability to quantify dynamic processes on a millisecond scale is exemplified with measurements of evaporating micrometer-sized water droplets.

© 2005 Optical Society of America

OCIS Codes
(170.1530) Medical optics and biotechnology : Cell analysis
(170.6920) Medical optics and biotechnology : Time-resolved imaging
(180.0180) Microscopy : Microscopy

Citation
Takahiro Ikeda, Gabriel Popescu, Ramachandra R. Dasari, and Michael S. Feld, "Hilbert phase microscopy for investigating fast dynamics in transparent systems," Opt. Lett. 30, 1165-1167 (2005)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-30-10-1165


Sort:  Author  |  Year  |  Journal  |  Reset

References

  1. D. J. Stephens and V. J. Allan, Science 300, 82 (2003).
  2. F. Zernike, Science 121, 345 (1955).
  3. F. H. Smith, Research (London) 8, 385 (1955).
  4. C. Yang, A. Wax, M. S. Hahn, K. Badizadegan, R. R. Dasari, and M. S. Feld, Opt. Lett. 26, 1271 (2001).
  5. G. A. Dunn and D. Zicha, in Cell Biology: A Laboratory Handbook, 2nd ed., J.Celis, ed. (Academic, San Diego, 1997), Calif., pp. 44-53.
  6. D. Paganin and K. A. Nugent, Phys. Rev. Lett. 80, 2586 (1998).
  7. G. Popescu, L. P. Deflores, J. C. Vaughan, K. Badizadegan, H. Iwai, R. R. Dasari, and M. S. Feld, Opt. Lett. 29, 2503 (2004).
  8. L. Miao, O. Vanderline, M. Stewart, T. M. Roberts, Science 300, 1405 (2003).
  9. A. E. Pelling, S. Sehati, E. B. Gralla, J. S. Valentine, J. K, Gimzewski, Science 305, 1147 (2004).
  10. D. A. Dombeck, M. Blanchard-Desce, and W. W. Webb, J. Neurosci. 24, 999 (2004).
  11. D. Gabor, J. Inst. Electr. Eng. 93, 329 (1946).
  12. M. Born and E. Wolf, Principles of Optics, 7th ed. (Cambridge U. Press, Cambridge, 1999), p. 557.
  13. G. Popescu and A. Dogariu, Phys. Rev. Lett. 88, 183902 (2002).
  14. M. Takeda, H. Ina, and S. Kobayashi, J. Opt. Soc. Am. 72, 156 (1982).
  15. K. Creath, Prog. Opt. 26, 349 (1988).
  16. G. Popescu, T. Ikeda, K. Badizadegan, R. R. Dasari, and M. S. Feld, are preparing a manuscript to be called "Inverted Hibert phase microscopy for nanoscale investigation of erythrocyte structure and dynamics."

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited