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Optics Letters

Optics Letters


  • Vol. 30, Iss. 11 — Jun. 1, 2005
  • pp: 1363–1365

Surface-sensitive polarized Raman spectroscopy of biological tissue

Zachary J. Smith and Andrew J. Berger  »View Author Affiliations

Optics Letters, Vol. 30, Issue 11, pp. 1363-1365 (2005)

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In a two-layer diffusing medium, polarized light directly backscattering off the superficial layer will partially retain its sense of polarization, whereas deeper-probing light will be increasingly depolarized by diffusion. This effect has been studied in both elastic scattering and fluorescence contexts. We apply this method to Raman scattering in two two-layer models with a highly diffusing lower layer of glucose powder and an upper layer of either clear plastic or chicken skin. We employ detection of orthogonal polarization states to generate a Raman spectrum of only the superficial layer by combining the orthogonal signals.

© 2005 Optical Society of America

OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.5660) Medical optics and biotechnology : Raman spectroscopy
(170.6930) Medical optics and biotechnology : Tissue

Zachary J. Smith and Andrew J. Berger, "Surface-sensitive polarized Raman spectroscopy of biological tissue," Opt. Lett. 30, 1363-1365 (2005)

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