OSA's Digital Library

Optics Letters

Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Vol. 30, Iss. 15 — Aug. 1, 2005
  • pp: 1968–1970

Spectral priors improve near-infrared diffuse tomography more than spatial priors

Ben Brooksby, Subhadra Srinivasan, Shudong Jiang, Hamid Dehghani, Brian W. Pogue, Keith D. Paulsen, John Weaver, Christine Kogel, and Steven P. Poplack  »View Author Affiliations


Optics Letters, Vol. 30, Issue 15, pp. 1968-1970 (2005)
http://dx.doi.org/10.1364/OL.30.001968


View Full Text Article

Acrobat PDF (244 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

We compare the benefits of spatial and spectral priors in near-infrared diffuse tomography image reconstruction. Although previous studies that incorporated anatomical spatial priors have shown improvement in algorithm convergence and resolution, our results indicate that functional parameter quantification by this approach can be suboptimal. The incorporation of a priori spectral information significantly improves the accuracy observed in recovered images. Specifically, phantom results show that the maximum total hemoglobin concentration ([Hb_T]) in a region of heterogeneity reached 91% of the true value compared to 63% using spatial priors. The combination of both priors produced results accurate to 98% of the true [Hb_T]. When both spatial and spectral priors were applied in a healthy volunteer, glandular tissue showed a higher [Hb_T], water fraction, and scattering power compared to adipose tissue.

© 2005 Optical Society of America

OCIS Codes
(110.3080) Imaging systems : Infrared imaging
(110.6960) Imaging systems : Tomography
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.3880) Medical optics and biotechnology : Medical and biological imaging

Citation
Ben Brooksby, Subhadra Srinivasan, Shudong Jiang, Hamid Dehghani, Brian W. Pogue, Keith D. Paulsen, John Weaver, Christine Kogel, and Steven P. Poplack, "Spectral priors improve near-infrared diffuse tomography more than spatial priors," Opt. Lett. 30, 1968-1970 (2005)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-30-15-1968

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited