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Optics Letters

Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Vol. 30, Iss. 18 — Sep. 15, 2005
  • pp: 2391–2393

Spectral domain second-harmonic optical coherence tomography

Marinko V. Sarunic, Brian E. Applegate, and Joseph A. Izatt  »View Author Affiliations


Optics Letters, Vol. 30, Issue 18, pp. 2391-2393 (2005)
http://dx.doi.org/10.1364/OL.30.002391


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Abstract

Optical coherence tomography (OCT) provides micrometer-scale structural imaging by coherent detection of backscattered light. Molecular contrast in OCT has been demonstrated using transient absorption, coherent anti-Stokes Raman scattering, and second-harmonic (SH) generation. The sensitivity of molecular contrast signals can be enhanced by use of Fourier domain techniques. We have constructed a spectrometer-based Fourier domain SH-OCT system for simultaneous acquisition of the fundamental and SH signals. We report a > 30 dB increase in SH sensitivity over a similar time domain SH-OCT system and demonstrate contrast between cartilage and bone using collagen as the contrast agent.

© 2005 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(190.4160) Nonlinear optics : Multiharmonic generation
(190.4710) Nonlinear optics : Optical nonlinearities in organic materials

Citation
Marinko V. Sarunic, Brian E. Applegate, and Joseph A. Izatt, "Spectral domain second-harmonic optical coherence tomography," Opt. Lett. 30, 2391-2393 (2005)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-30-18-2391

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