Controlled induction, enhancement, and guidance of neuronal growth cones by use of line optical tweezers
Optics Letters, Vol. 30, Issue 19, pp. 2596-2598 (2005)
http://dx.doi.org/10.1364/OL.30.002596
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Abstract
We report an optical tweezers based approach for efficient and controlled manipulation of neuronal growth cones. The approach exploits asymmetric transverse gradient force created in a line optical tweezers to transport actin monomers in the desired growth direction. With this approach induction of artificial growth cones from the neuronal cell body and enhancement of the growth rate of the natural growth cones have been achieved. The use of this approach to bring two growth cones into close proximity for establishing a neuronal connection is also discussed.
© 2005 Optical Society of America
OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.4520) Medical optics and biotechnology : Optical confinement and manipulation
ToC Category:
Medical Optics and Biotechnology
Citation
Samarendra K. Mohanty, Mrinalini Sharma, Mitradas M. Panicker, and Pradeep K. Gupta, "Controlled induction, enhancement, and guidance of neuronal growth cones by use of line optical tweezers," Opt. Lett. 30, 2596-2598 (2005)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-30-19-2596
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