Blood flow contrast between tumor and normal tissues in patients with malignant and benign breast cancer was measured by diffuse optical correlation methods. The measurements were carried out with a hand-held optical probe that was manually scanned over the tumor-bearing breast. Increased blood flow was observed in tumor regions relative to healthy tissue, and control subjects did not exhibit significant blood flow heterogeneity. The measurements introduce a new optical contrast for diffuse optical mammography.
© 2005 Optical Society of America
Medical Optics and Biotechnology
Turgut Durduran, Regine Choe, Guoqiang Yu, Chao Zhou, Julia C. Tchou, Brian J. Czerniecki, and Arjun G. Yodh, "Diffuse optical measurement of blood flow in breast tumors," Opt. Lett. 30, 2915-2917 (2005)