Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Molecularly sensitive optical coherence tomography

Not Accessible

Your library or personal account may give you access

Abstract

Molecular contrast in optical coherence tomography (OCT) is demonstrated by use of coherent anti-Stokes Raman scattering (CARS) for molecular sensitivity. Femtosecond laser pulses are focused into a sample by use of a low-numerical-aperture lens to generate CARS photons, and the backreflected CARS signal is interferometrically measured. With the chemical selectivity provided by CARS and the advanced imaging capabilities of OCT, this technique may be useful for molecular contrast imaging in biological tissues. CARS can be generated and interferometrically measured over at least 600 µm of the depth of field of a low-numerical-aperture objective.

© 2005 Optical Society of America

Full Article  |  PDF Article
More Like This
Spectral domain second-harmonic optical coherence tomography

Marinko V. Sarunic, Brian E. Applegate, and Joseph A. Izatt
Opt. Lett. 30(18) 2391-2393 (2005)

Nonlinear optical contrast enhancement for optical coherence tomography

Claudio Vinegoni, Jeremy S. Bredfeldt, Daniel L. Marks, and Stephen A. Boppart
Opt. Express 12(2) 331-341 (2004)

Second-harmonic optical coherence tomography

Yi Jiang, Ivan Tomov, Yimin Wang, and Zhongping Chen
Opt. Lett. 29(10) 1090-1092 (2004)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (4)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved