The capability of photothermal (PT) microscopy to image moving, unlabeled cells in real time in vivo is demonstrated in a study of circulating red and white blood cells in blood and lymph microvessels of rat mesentery. Potential applications of this optical tool, called PT flow cytometry, are discussed.
© 2005 Optical Society of America
(170.0110) Medical optics and biotechnology : Imaging systems
(170.0180) Medical optics and biotechnology : Microscopy
(170.1530) Medical optics and biotechnology : Cell analysis
(170.6920) Medical optics and biotechnology : Time-resolved imaging
Vladimir P. Zharov, Ekaterina I. Galanzha, and Valery V. Tuchin, "Photothermal image flow cytometry in vivo," Opt. Lett. 30, 628-630 (2005)