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Optics Letters

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  • Vol. 30, Iss. 9 — May. 1, 2005
  • pp: 1021–1023

Miniature fiber-optic multicavity Fabry-Perot interferometric biosensor

Yan Zhang, Helen Shibru, Kristie L. Cooper, and Anbo Wang  »View Author Affiliations


Optics Letters, Vol. 30, Issue 9, pp. 1021-1023 (2005)
http://dx.doi.org/10.1364/OL.30.001021


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Abstract

A fiber-optic sensor is designed based on multicavity Fabry-Perot interferometry for the study of optical thickness in self-assembled thin-film layers. This miniature sensor is applicable not only to the measurement of self-assembled polyelectrolyte layers but also to the immobilization of proteins such as immunoglobulin G (IgG). The binding of IgG and the corresponding antigen is observed, and the nonspecific binding characteristics are investigated. The optical thickness changes are used to evaluate the immobilization of the IgG and the immunological activities of the immobilized layers.

© 2005 Optical Society of America

OCIS Codes
(060.2370) Fiber optics and optical communications : Fiber optics sensors
(120.2230) Instrumentation, measurement, and metrology : Fabry-Perot
(310.1860) Thin films : Deposition and fabrication

Citation
Yan Zhang, Helen Shibru, Kristie L. Cooper, and Anbo Wang, "Miniature fiber-optic multicavity Fabry-Perot interferometric biosensor," Opt. Lett. 30, 1021-1023 (2005)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-30-9-1021


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