Retinal cone mosaic imaged with transverse scanning optical coherence tomography
Optics Letters, Vol. 31, Issue 12, pp. 1821-1823 (2006)
http://dx.doi.org/10.1364/OL.31.001821
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Abstract
We improved our recently reported retinal OCT system based on transverse priority scanning to achieve high resolution in both the transverse and the axial directions. The implementation of an additional SLO channel enables precise on-line focusing. The system enables imaging of the human retinal cone mosaic off the foveal center without adaptive optics. We demonstrate, for what is believed to be the first time, cone mosaic imaging simultaneously in the scanning laser ophthalmoscope and optical coherence tomography (OCT) channels. OCT B-scan images demonstrate that the cone mosaic is observable in two adjacent layers. Furthermore, we present what are believed to be the first C-scan OCT images of the cone mosaic and show that the major part of light backscattered from below the photoreceptor layer is not guided back toward the pupil by the photoreceptors.
© 2006 Optical Society of America
OCIS Codes
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(330.5310) Vision, color, and visual optics : Vision - photoreceptors
ToC Category:
Medical Optics and Biotechnology
History
Original Manuscript: January 18, 2006
Revised Manuscript: March 17, 2006
Manuscript Accepted: March 20, 2006
Virtual Issues
Vol. 1, Iss. 7 Virtual Journal for Biomedical Optics
Citation
Michael Pircher, Bernhard Baumann, Erich Götzinger, and Christoph K. Hitzenberger, "Retinal cone mosaic imaged with transverse scanning optical coherence tomography," Opt. Lett. 31, 1821-1823 (2006)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-31-12-1821
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