Multiwavelength optoacoustic system for noninvasive monitoring of cerebral venous oxygenation: a pilot clinical test in the internal jugular vein
Optics Letters, Vol. 31, Issue 12, pp. 1827-1829 (2006)
http://dx.doi.org/10.1364/OL.31.001827
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Abstract
A noninvasive, high-resolution optoacoustic technique is a promising alternative to currently used invasive methods of brain oxygenation monitoring. We present the results of our pilot clinical test of this technique in healthy volunteers. Multiwavelength optoacoustic measurements (with nanosecond optical parametric oscillator as a source of radiation) were performed on the area of the neck overlying the internal jugular vein, a deeply located large vein that drains blood from the brain and from extracranial tissues. Optoacoustic signals induced in venous blood were measured with high resolution and signal-to-noise ratio despite the presence of a thick layer of overlying tissue (up to
© 2006 Optical Society of America
OCIS Codes
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.1460) Medical optics and biotechnology : Blood gas monitoring
(170.1610) Medical optics and biotechnology : Clinical applications
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
ToC Category:
Medical Optics and Biotechnology
History
Original Manuscript: February 2, 2006
Revised Manuscript: March 27, 2006
Manuscript Accepted: April 6, 2006
Virtual Issues
Vol. 1, Iss. 7 Virtual Journal for Biomedical Optics
Citation
Yuriy Y. Petrov, Irina Y. Petrova, Igor A. Patrikeev, Rinat O. Esenaliev, and Donald S. Prough, "Multiwavelength optoacoustic system for noninvasive monitoring of cerebral venous oxygenation: a pilot clinical test in the internal jugular vein," Opt. Lett. 31, 1827-1829 (2006)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-31-12-1827
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