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Optics Letters

Optics Letters


  • Editor: Anthony J. Campillo
  • Vol. 31, Iss. 2 — Jan. 15, 2006
  • pp: 241–243

Heterodyne coherent anti-Stokes Raman scattering (CARS) imaging

Eric O. Potma, Conor L. Evans, and X. Sunney Xie  »View Author Affiliations

Optics Letters, Vol. 31, Issue 2, pp. 241-243 (2006)

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We have achieved rapid nonlinear vibrational imaging free of nonresonant background with heterodyne coherent anti-Stokes Raman scattering (CARS) interferometric microscopy. This technique completely separates the real and imaginary responses of nonlinear susceptibility χ ( 3 ) and yields a signal that is linear in the concentration of vibrational modes. We show that heterodyne CARS microscopy permits the detection of weak vibrational resonances that are otherwise overshadowed by the strong interference of the nonresonant background.

© 2006 Optical Society of America

OCIS Codes
(180.6900) Microscopy : Three-dimensional microscopy
(190.5650) Nonlinear optics : Raman effect

ToC Category:
Nonlinear Optics

Virtual Issues
Vol. 1, Iss. 2 Virtual Journal for Biomedical Optics

Eric O. Potma, Conor L. Evans, and X. Sunney Xie, "Heterodyne coherent anti-Stokes Raman scattering (CARS) imaging," Opt. Lett. 31, 241-243 (2006)

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  1. J. X. Cheng and X. S. Xie, J. Phys. Chem. B 108, 827 (2004). [CrossRef]
  2. X. L. Nan, J. X. Cheng, and X. S. Xie, J. Lipid Res. 44, 2202 (2003). [CrossRef] [PubMed]
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  4. J. X. Cheng, L. D. Book, and X. S. Xie, Opt. Lett. 26, 1341 (2001). [CrossRef]
  5. A. Volkmer, L. D. Book, and X. S. Xie, Appl. Phys. Lett. 80, 1505 (2002). [CrossRef]
  6. R. W. Hellwarth, in Progress in Quantum Electronics, J.H.Sanders and S.Stenholm, eds. (Pergamon, 1977), pp. 1-68.
  7. C. L. Evans, E. O. Potma, and X. S. Xie, Opt. Lett. 29, 2923 (2004). [CrossRef]

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