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Optics Letters

Optics Letters


  • Editor: Anthony J. Campillo
  • Vol. 31, Iss. 23 — Dec. 1, 2006
  • pp: 3465–3467

Quantitative modeling of laser speckle imaging

Pavel Zakharov, Andreas Völker, Alfred Buck, Bruno Weber, and Frank Scheffold  »View Author Affiliations

Optics Letters, Vol. 31, Issue 23, pp. 3465-3467 (2006)

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We have analyzed the image formation and dynamic properties in laser speckle imaging (LSI) both experimentally and with Monte Carlo simulation. We show for the case of a liquid inclusion that the spatial resolution and the signal itself are both significantly affected by scattering from the turbid environment. Multiple scattering leads to blurring of the dynamic inhomogeneity as detected by LSI. The presence of a nonfluctuating component of scattered light results in the significant increase in the measured image contrast and complicates the estimation of the relaxation time. We present a refined processing scheme that allows a correct estimation of the relaxation time from LSI data.

© 2006 Optical Society of America

OCIS Codes
(030.6140) Coherence and statistical optics : Speckle
(030.6600) Coherence and statistical optics : Statistical optics
(170.0110) Medical optics and biotechnology : Imaging systems
(170.3880) Medical optics and biotechnology : Medical and biological imaging

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: June 1, 2006
Revised Manuscript: July 26, 2006
Manuscript Accepted: August 7, 2006
Published: November 9, 2006

Virtual Issues
Vol. 2, Iss. 1 Virtual Journal for Biomedical Optics

Pavel Zakharov, Andreas Völker, Alfred Buck, Bruno Weber, and Frank Scheffold, "Quantitative modeling of laser speckle imaging," Opt. Lett. 31, 3465-3467 (2006)

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