We report on the quantitative influence of speckles in laser Doppler perfusion imaging. The influence of speckles on the signal amplitude and on the Doppler spectrum is demonstrated experimentally for particle suspensions with different scattering levels and various beam widths. It is shown that the type of tissue affects the instrumental response through the effect of lateral light diffusion on the number of speckles involved in the detection process. These effects are largest for narrow beams.
© 2006 Optical Society of America
Medical Optics and Biotechnology
Original Manuscript: November 4, 2005
Manuscript Accepted: November 4, 2005
Vol. 1, Iss. 3 Virtual Journal for Biomedical Optics
V. Rajan, B. Varghese, T. G. van Leeuwen, and W. Steenbergen, "Speckles in laser Doppler perfusion imaging," Opt. Lett. 31, 468-470 (2006)