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Optics Letters

Optics Letters


  • Editor: Anthony J. Campillo
  • Vol. 31, Iss. 4 — Feb. 15, 2006
  • pp: 480–482

Fourier-transform coherent anti-Stokes Raman scattering microscopy

Jennifer P. Ogilvie, Emmanuel Beaurepaire, Antigoni Alexandrou, and Manuel Joffre  »View Author Affiliations

Optics Letters, Vol. 31, Issue 4, pp. 480-482 (2006)

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We report a novel Fourier-transform-based implementation of coherent anti-Stokes Raman scattering (CARS) microscopy. The method employs a single femtosecond laser source and a Michelson interferometer to create two pulse replicas that are fed into a scanning multiphoton microscope. By varying the time delay between the pulses, we time-resolve the CARS signal, permitting easy removal of the nonresonant background while providing high resolution, spectrally resolved images of CARS modes over the laser bandwidth ( 1500 cm 1 ) . We demonstrate the method by imaging polystyrene beads in solvent.

© 2006 Optical Society of America

OCIS Codes
(020.1670) Atomic and molecular physics : Coherent optical effects
(020.4180) Atomic and molecular physics : Multiphoton processes
(170.5660) Medical optics and biotechnology : Raman spectroscopy
(180.6900) Microscopy : Three-dimensional microscopy
(300.6410) Spectroscopy : Spectroscopy, multiphoton
(300.6450) Spectroscopy : Spectroscopy, Raman

ToC Category:

Original Manuscript: September 13, 2005
Manuscript Accepted: October 14, 2005

Virtual Issues
Vol. 1, Iss. 3 Virtual Journal for Biomedical Optics

Jennifer P. Ogilvie, Emmanuel Beaurepaire, Antigoni Alexandrou, and Manuel Joffre, "Fourier-transform coherent anti-Stokes Raman scattering microscopy," Opt. Lett. 31, 480-482 (2006)

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