OSA's Digital Library

Optics Letters

Optics Letters


  • Editor: Anthony J. Campillo
  • Vol. 31, Iss. 9 — May. 1, 2006
  • pp: 1268–1270

MEMS-based adaptive optics scanning laser ophthalmoscopy

Yuhua Zhang, Siddharth Poonja, and Austin Roorda  »View Author Affiliations

Optics Letters, Vol. 31, Issue 9, pp. 1268-1270 (2006)

View Full Text Article

Enhanced HTML    Acrobat PDF (468 KB)

Browse Journals / Lookup Meetings

Browse by Journal and Year


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools



We have developed a compact, robust adaptive optics (AO) scanning laser ophthalmoscope using a microelectromechanical (MEMS) deformable mirror (DM). Facilitated with a Shack–Hartmann wavefront sensor, the MEMS-DM-based AO operates a closed-loop modal wave aberration correction for the human eye and reduces wave aberrations in most eyes to below 0.1 μ m rms. Lateral resolution is enhanced, and images reveal a clear cone mosaic near the foveal center. The significant increase in throughput allows for a confocal pinhole whose diameter is less than the Airy disc of the collection lens, thereby fully exploiting the axial resolution capabilities of the system.

© 2006 Optical Society of America

OCIS Codes
(010.1080) Atmospheric and oceanic optics : Active or adaptive optics
(170.1790) Medical optics and biotechnology : Confocal microscopy
(230.3990) Optical devices : Micro-optical devices
(330.4460) Vision, color, and visual optics : Ophthalmic optics and devices

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: January 6, 2006
Manuscript Accepted: January 19, 2006

Virtual Issues
Vol. 1, Iss. 6 Virtual Journal for Biomedical Optics

Yuhua Zhang, Siddharth Poonja, and Austin Roorda, "MEMS-based adaptive optics scanning laser ophthalmoscopy," Opt. Lett. 31, 1268-1270 (2006)

Sort:  Author  |  Year  |  Journal  |  Reset  


  1. R. H. Webb and G. W. Hughes, IEEE Trans. Biomed. Eng. 28, 488 (1981). [CrossRef] [PubMed]
  2. R. H. Webb, G. W. Hughes, and F. C. Delori, Appl. Opt. 26, 1492 (1987). [CrossRef] [PubMed]
  3. R. H. Webb, Rep. Prog. Phys. 59, 427 (1996). [CrossRef]
  4. T. Wilson and C. J. R. Sheppard, Theory and Practice of Scanning Optical Microscopy (Academic, 1984).
  5. A. Roorda, F. Romero-Borja, W. J. Donnelly III, H. Queener, T. J. Hebert, and M. C. W. Campbell, Opt. Express 10, 405 (2002). [PubMed]
  6. F. Romero-Borja, K. Venkateswaran, A. Roorda, and T. J. Hebert, Appl. Opt. 44, 4032 (2005). [CrossRef] [PubMed]
  7. A. W. Dreher, J. F. Bille, and R. N. Weinreb, Appl. Opt. 28, 804 (1989). [CrossRef] [PubMed]
  8. J. Liang, D. R. Williams, and D. T. Miller, J. Opt. Soc. Am. A 14, 2884 (1997). [CrossRef]
  9. H. Hofer, L. Chen, G. Y. Yoon, B. Singer, Y. Yamauchi, and D. R. Williams, Opt. Express 8, 631 (2001). [CrossRef] [PubMed]
  10. A. Pallikaris, D. R. Williams, and H. Hofer, Invest. Ophthalmol. Visual Sci. 44, 4580 (2003). [CrossRef]
  11. E. J. Fernandez, I. Iglesias, and P. Artal, Opt. Lett. 26, 746 (2001). [CrossRef]
  12. B. Hermann, E. J. Fernandez, A. Unterhuber, H. Sattmann, A. F. Fercher, W. Drexler, P. M. Prieto, and P. Artal, Opt. Lett. 29, 2142 (2004). [CrossRef] [PubMed]
  13. F. Vargas-Martin, P. M. Prieto, and P. Artal, J. Opt. Soc. Am. A 14, 2884 (1997). [CrossRef]
  14. N. Doble, G. Yoon, P. Bierden, L. Chen, S. Olivier, and D. R. Williams, Opt. Lett. 27, 1537 (2002). [CrossRef]
  15. T. G. Bifano, J. A. Perreault, P. A. Bierden, and C. E. Dimas, in Proc. SPIE 4825, 10 (2002). [CrossRef]
  16. D. T. Miller, L. N. Thibos, and X. Hong, Opt. Express 13, 275 (2005). [CrossRef] [PubMed]
  17. A. Roorda and Y. Zhang, Invest. Ophthalmol. Visual Sci. 46, E-Abstract 2433 (2005). [CrossRef]
  18. C. Vogel, D. Arathorn, A. Roorda, and A. Parker, Opt. Express 14, 487 (2006). [CrossRef] [PubMed]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


Fig. 1 Fig. 2 Fig. 3
Fig. 4 Fig. 5

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited