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Experimental study of sensitivity enhancement in surface plasmon resonance biosensors by use of periodic metallic nanowires

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Abstract

We have experimentally confirmed sensitivity enhancement of a nanowire-based surface plasmon resonance (SPR) sensor structure. Gold nanowires with periods of 200 and 500nm were fabricated, respectively, by electron-beam and interference lithography on a gold/SF10 substrate. Sensitivity enhancement was measured to be 44% compared with a conventional thin-film-based SPR structure for nanowires of 200nm period and 31% for 500nm when evaluated using ethanol at a varied concentration. This result is consistent with numerical data. Surface roughness is responsible for sensitivity reduction by more than 10%. More significant sensitivity improvement can be achieved by inducing strong localized plasmon coupling with finer nanowires.

© 2007 Optical Society of America

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