OSA's Digital Library

Optics Letters

Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Editor: Anthony J. Campillo
  • Vol. 32, Iss. 16 — Aug. 15, 2007
  • pp: 2285–2287

Multi-optical-wavelength ultrasound-modulated optical tomography: a phantom study

Chulhong Kim and Lihong V. Wang  »View Author Affiliations


Optics Letters, Vol. 32, Issue 16, pp. 2285-2287 (2007)
http://dx.doi.org/10.1364/OL.32.002285


View Full Text Article

Enhanced HTML    Acrobat PDF (239 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

We used multiple optical wavelengths to study ultrasound-modulated optical tomography (UOT) in tissue phantoms. By using intense acoustic bursts and a CCD camera-based speckle contrast detection technique, we observed variations of the ultrasound-modulated signal at various optical absorptions. The experimental variations were found to be highly correlated with predictions from Monte Carlo simulations. By irradiating the sample at two optical wavelengths, we quantitatively estimated the total concentration and the concentration ratio of double dyes in objects embedded in tissue phantoms. The results suggest that UOT can potentially provide noninvasive functional imaging of the total concentration and oxygen saturation of hemoglobin in biological tissue.

© 2007 Optical Society of America

OCIS Codes
(030.1670) Coherence and statistical optics : Coherent optical effects
(110.6150) Imaging systems : Speckle imaging
(110.7170) Imaging systems : Ultrasound
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.6480) Medical optics and biotechnology : Spectroscopy, speckle

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: April 12, 2007
Revised Manuscript: July 2, 2007
Manuscript Accepted: July 6, 2007
Published: August 2, 2007

Virtual Issues
Vol. 2, Iss. 9 Virtual Journal for Biomedical Optics

Citation
Chulhong Kim and Lihong V. Wang, "Multi-optical-wavelength ultrasound-modulated optical tomography: a phantom study," Opt. Lett. 32, 2285-2287 (2007)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-32-16-2285


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. I. Vanzetta and A. Grinvald, Science 286, 1555 (1999). [CrossRef] [PubMed]
  2. C. Menon and D. L. Frake, Cancer Lett. 221, 225 (2005). [CrossRef] [PubMed]
  3. J. P. Culver, A. M. Siegel, J. J. Stott, and D. A. Boas, Opt. Lett. 28, 2016 (2003). [CrossRef]
  4. X. Wang, Y. Pang, G. Ku, X. Xie, G. Stoica, and L.-H. Wang, Nat. Biotechnol. 21, 803 (2003). [CrossRef] [PubMed]
  5. H. F. Zhang, K. Maslov, G. Stoica, and L.-H. Wang, Nat. Biotechnol. 24, 848 (2006). [CrossRef] [PubMed]
  6. L.-H. Wang, S. L. Jacques, and X. Zhao, Opt. Lett. 20, 629 (1995). [CrossRef] [PubMed]
  7. W. Leutz and G. Maret, Physica B 204, 14 (1995). [CrossRef]
  8. L.-H. V. Wang, Phys. Rev. Lett. 87, 043903 (2001). [CrossRef] [PubMed]
  9. S. Sakadzic and L.-H. V. Wang, Phys. Rev. E 74, 036618 (2006). [CrossRef]
  10. S. Leveque, A. C. Boccara, M. Lebec, and H. Saint-Jalmes, Opt. Lett. 24, 181 (1999). [CrossRef]
  11. S. Sakadzic and L.-H. V. Wang, Opt. Lett. 29, 2770 (2004). [CrossRef] [PubMed]
  12. T. W. Murray, L. Sui, G. Maguluri, R. A. Roy, A. Nieva, F. Blonigen, and C. A. DiMarzio, Opt. Lett. 29, 2509 (2004). [CrossRef] [PubMed]
  13. C. Kim, R. J. Zemp, and L.-H. V. Wang, Opt. Lett. 31, 2423 (2006). [CrossRef] [PubMed]
  14. R. J. Zemp, S. Sakadzic, and L.-H. V. Wang, Phys. Rev. E 73, 061920 (2006). [CrossRef]
  15. D. Dalecki, Biomed. Eng. (NY) 6, 18.1 (2004).

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

Figures

Fig. 1 Fig. 2 Fig. 3
 

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited