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Optics Letters

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  • Editor: Alan E. Willner
  • Vol. 33, Iss. 12 — Jun. 15, 2008
  • pp: 1285–1287

Parallel frequency-domain optical coherence tomography scatter-mode imaging of the hamster cheek pouch using a thermal light source

R. N. Graf, W. J. Brown, and A. Wax  »View Author Affiliations


Optics Letters, Vol. 33, Issue 12, pp. 1285-1287 (2008)
http://dx.doi.org/10.1364/OL.33.001285


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Abstract

We use a parallel frequency-domain optical coherence tomography (FDOCT) system to generate a scatter-mode image of the hamster cheek pouch epithelium. To our knowledge, this is the first optical coherence tomography (OCT) image of a biological sample obtained using a thermal light source in the frequency domain. The system employs an imaging spectrometer to acquire depth-resolved profiles from adjacent spatial points without the need for any scanning. To enable this imaging modality, we have considered that signals originating from multiple depths combine in a different manner in FDOCT compared to time-domain optical coherence tomography (TDOCT). Because a multicomponent FDOCT signal is a coherent sum, it is necessary to limit the number of modes that contribute to the detected signal. Conversely, multicomponent TDOCT signals can be represented as incoherent sums, where increasing the number of modes improves the signal.

© 2008 Optical Society of America

OCIS Codes
(030.1640) Coherence and statistical optics : Coherence
(120.3180) Instrumentation, measurement, and metrology : Interferometry
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Coherence and Statistical Optics

History
Original Manuscript: March 24, 2008
Manuscript Accepted: April 22, 2008
Published: June 3, 2008

Virtual Issues
Vol. 3, Iss. 7 Virtual Journal for Biomedical Optics

Citation
R. N. Graf, W. J. Brown, and A. Wax, "Parallel frequency-domain optical coherence tomography scatter-mode imaging of the hamster cheek pouch using a thermal light source," Opt. Lett. 33, 1285-1287 (2008)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-33-12-1285


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