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Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Editor: Alan E. Willner
  • Vol. 33, Iss. 12 — Jun. 15, 2008
  • pp: 1324–1326

Miniaturized probe based on a microelectromechanical system mirror for multiphoton microscopy

Woonggyu Jung, Suo Tang, Daniel T. McCormic, Tiquiang Xie, Yeh-Chan Ahn, Jianping Su, Ivan V. Tomov, Tatiana B. Krasieva, Bruce J. Tromberg, and Zhongping Chen  »View Author Affiliations


Optics Letters, Vol. 33, Issue 12, pp. 1324-1326 (2008)
http://dx.doi.org/10.1364/OL.33.001324


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Abstract

A factor that limits the use of multiphoton microscopy (MPM) in clinical and preclinical studies is the lack of a compact and flexible probe. We report on a miniaturized MPM probe employing a microelectromechanical system (MEMS) scanning mirror and a double-clad photonic crystal fiber (DCPCF). The use of a MEMS mirror and a DCPCF provides many advantages, such as size reduction, rapid and precise scanning, efficient delivery of short pulses, and high collection efficiency of fluorescent signals. The completed probe was 1 cm in outer diameter and 14 cm in length. The developed probe was integrated into an MPM system and used to image fluorescent beads, paper, and biological specimens.

© 2008 Optical Society of America

OCIS Codes
(170.2520) Medical optics and biotechnology : Fluorescence microscopy
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(190.4180) Nonlinear optics : Multiphoton processes

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: February 29, 2008
Manuscript Accepted: April 8, 2008
Published: June 11, 2008

Virtual Issues
Vol. 3, Iss. 7 Virtual Journal for Biomedical Optics

Citation
Woonggyu Jung, Suo Tang, Daniel T. McCormic, Tiquiang Xie, Yeh-Chan Ahn, Jianping Su, Ivan V. Tomov, Tatiana B. Krasieva, Bruce J. Tromberg, and Zhongping Chen, "Miniaturized probe based on a microelectromechanical system mirror for multiphoton microscopy," Opt. Lett. 33, 1324-1326 (2008)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-33-12-1324


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