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Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Editor: Alan E. Willner
  • Vol. 33, Iss. 8 — Apr. 15, 2008
  • pp: 836–838

Quantitative retinal-blood flow measurement with three-dimensional vessel geometry determination using ultrahigh-resolution Doppler optical coherence angiography

Shuichi Makita, Tapio Fabritius, and Yoshiaki Yasuno  »View Author Affiliations


Optics Letters, Vol. 33, Issue 8, pp. 836-838 (2008)
http://dx.doi.org/10.1364/OL.33.000836


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Abstract

Retinal blood flow quantification by retinal vessel segmentation with Doppler optical coherence angiography is presented. Vessel diameter, orientation, and position are determined in an en face vessel image and two representative cross-sectional flow images of the vessel. Absolute blood flow velocity is calculated with the help of the measured Doppler frequency shift and determined vessel angle. The volumetric flow rate is obtained with the position and the region of the vessel lumen. The volumetric blood flow rate of retinal arteries before and after a bifurcation is verified in a healthy human eye.

© 2008 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(170.3340) Medical optics and biotechnology : Laser Doppler velocimetry
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: November 1, 2007
Revised Manuscript: January 17, 2008
Manuscript Accepted: February 15, 2008
Published: April 14, 2008

Virtual Issues
Vol. 3, Iss. 5 Virtual Journal for Biomedical Optics

Citation
Shuichi Makita, Tapio Fabritius, and Yoshiaki Yasuno, "Quantitative retinal-blood flow measurement with three-dimensional vessel geometry determination using ultrahigh-resolution Doppler optical coherence angiography," Opt. Lett. 33, 836-838 (2008)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-33-8-836


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References

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