OSA's Digital Library

Optics Letters

Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Editor: Alan E. Willner
  • Vol. 34, Iss. 12 — Jun. 15, 2009
  • pp: 1771–1773

Laser-scanning optical-resolution photoacoustic microscopy

Zhixing Xie, Shuliang Jiao, Hao F. Zhang, and Carmen A. Puliafito  »View Author Affiliations


Optics Letters, Vol. 34, Issue 12, pp. 1771-1773 (2009)
http://dx.doi.org/10.1364/OL.34.001771


View Full Text Article

Enhanced HTML    Acrobat PDF (264 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

We have developed a laser-scanning optical-resolution photoacoustic microscopy method that can potentially fuse with existing optical microscopic imaging modalities. To acquire an image, the ultrasonic transducer is kept stationary during data acquisition, and only the laser light is raster scanned by an xy galvanometer scanner. A lateral resolution of 7.8 μ m and a circular field of view with a diameter of 6 mm were achieved in an optically clear medium. Using a laser system working at a pulse repetition rate of 1024 Hz , the data acquisition time for an image consisting of 256 × 256   pixels was less than 2 min.

© 2009 Optical Society of America

OCIS Codes
(110.0180) Imaging systems : Microscopy
(110.5120) Imaging systems : Photoacoustic imaging

ToC Category:
Imaging Systems

History
Original Manuscript: January 27, 2009
Revised Manuscript: March 31, 2009
Manuscript Accepted: April 23, 2009
Published: June 2, 2009

Virtual Issues
Vol. 4, Iss. 8 Virtual Journal for Biomedical Optics

Citation
Zhixing Xie, Shuliang Jiao, Hao F. Zhang, and Carmen A. Puliafito, "Laser-scanning optical-resolution photoacoustic microscopy," Opt. Lett. 34, 1771-1773 (2009)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-34-12-1771


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. D. A. Sipkins, X. Wei, J. W. Wu, J. M. Runnels, D. Côté, T. K. Means, A. D. Luster, D. T. Scadden, and C. P. Lin, Nature 435, 969 (2005). [CrossRef] [PubMed]
  2. C. A. Patil, N. Bosschaart, M. D. Keller, T. G. van Leeuwen, and A. Mahadevan-Jansen, Opt. Lett. 33, 1135 (2008). [CrossRef] [PubMed]
  3. S. Tang, T. B. Krasieva, Z. Chen, and B. J. Tromberg, J. Biomed. Opt. 11, 020502 (2006). [CrossRef] [PubMed]
  4. A. A. Oraevsky and A. A. Karabutov, in Biomedical Photonics Handbook, T.Vo-Dinh, ed. (CRC Press, 2003), Vol. PM125, Chap. 34.
  5. X. Wang, Y. Pang, G. Ku, X. Xie, G. Stoica, and L. V. Wang, Nat. Biotechnol. 25, 114 (2003).
  6. H. F. Zhang, K. Maslov, and L. V. Wang, Nat. Protocols 4, 797 (2007). [CrossRef]
  7. H. F. Zhang, K. Maslov, G. Stoica, and L. V. Wang, Nat. Biotechnol. 24, 848 (2006). [CrossRef] [PubMed]
  8. K. Maslov, H. F. Zhang, S. Hu, and L. V. Wang, Opt. Lett. 33, 929 (2008). [CrossRef] [PubMed]
  9. V. P. Zharov, E. I. Galanzha, E. V. Shashkov, N. G. Khlebtsov, and V. V. Tuchin, Opt. Lett. 31, 3623 (2008). [CrossRef]
  10. Laser Institute of America, American National Standard for Safe Use of Lasers ANSI Z136.1-2007 (American National Standards Institute, Inc., 2007).

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

Figures

Fig. 1 Fig. 2 Fig. 3
 

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited