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Optics Letters


  • Editor: Alan E. Willner
  • Vol. 34, Iss. 16 — Aug. 15, 2009
  • pp: 2393–2395

Differential-absorption photoacoustic imaging

Sheng-Wen Huang, Janet F. Eary, Congxian Jia, Lingyun Huang, Shai Ashkenazi, and Matthew O’Donnell  »View Author Affiliations

Optics Letters, Vol. 34, Issue 16, pp. 2393-2395 (2009)

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We present differential-absorption photoacoustic imaging, which detects the difference between transient and ground-state absorption, for contrast enhancement based on suppressing undesired objects. Two tubes were imaged. One contains a Pt(II) octaethylporphine (PtOEP) dye solution and serves as an object of interest, while the other contains an IR-783 (from Sigma-Aldrich) dye solution and serves as an object to suppress. Although the IR-783 tube dominates the conventional photoacoustic image, it is suppressed by 43 dB and consequently significantly overwhelmed by the PtOEP tube in the differential-absorption photoacoustic image. Imaging depth in this mode is also discussed.

© 2009 Optical Society of America

OCIS Codes
(000.2170) General : Equipment and techniques
(110.0110) Imaging systems : Imaging systems
(110.5120) Imaging systems : Photoacoustic imaging
(170.0110) Medical optics and biotechnology : Imaging systems
(170.3650) Medical optics and biotechnology : Lifetime-based sensing
(170.5120) Medical optics and biotechnology : Photoacoustic imaging

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: May 12, 2009
Revised Manuscript: July 10, 2009
Manuscript Accepted: July 15, 2009
Published: August 4, 2009

Virtual Issues
Vol. 4, Iss. 10 Virtual Journal for Biomedical Optics

Sheng-Wen Huang, Janet F. Eary, Congxian Jia, Lingyun Huang, Shai Ashkenazi, and Matthew O'Donnell, "Differential-absorption photoacoustic imaging," Opt. Lett. 34, 2393-2395 (2009)

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  1. A. A. Oraevsky, S. L. Jacques, R. O. Esenaliev, and F. K. Tittel, Proc. SPIE 2134A, 122 (1994).
  2. X. Wang, Y. Pang, G. Ku, X. Xie, G. Stoica, and L. V. Wang, Nat. Biotechnol. 21, 803 (2003). [CrossRef] [PubMed]
  3. S. Sethuraman, S. R. Aglyamov, J. H. Amirian, R. W. Smalling, and S. Y. Emelianov, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 54, 978 (2007). [CrossRef] [PubMed]
  4. G. Kim, S.-W. Huang, K. C. Day, M. O'Donnell, R. R. Agayan, M. A. Day, R. Kopelman, and S. Ashkenazi, J. Biomed. Opt. 12, 044020 (2007). [CrossRef] [PubMed]
  5. P.-C. Li, C.-W. Wei, C.-K. Liao, C.-D. Chen, K.-C. Pao, C.-R. C. Wang, Y.-N. Wu, and D.-B. Shieh, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 54, 1642 (2007). [CrossRef] [PubMed]
  6. A. K. Bansal, W. Holzer, A. Penzkofer, and T. Tsuboi, Chem. Phys. 330, 118 (2006). [CrossRef]
  7. S. Ashkenazi, S.-W. Huang, T. Horvath, Y.-E. L. Koo, and R. Kopelman, J. Biomed. Opt. 13, 034023 (2008). [CrossRef] [PubMed]
  8. C. Li, T. R. Greenwood, Z. M. Bhujwalla, and K. Glunde, Org. Lett. 8, 3623 (2006). [CrossRef] [PubMed]
  9. I. Dunphy, S. A. Vinogradov, and D. F. Wilson, Anal. Biochem. 310, 191 (2002). [CrossRef] [PubMed]

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