Single-camera sequential-scan-based polarization-sensitive SDOCT for retinal imaging
Optics Letters, Vol. 34, Issue 2, pp. 205-207 (2009)
http://dx.doi.org/10.1364/OL.34.000205
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Abstract
A single-camera, high-speed, polarization-sensitive, spectral-domain optical-coherence-tomography system was developed to measure the polarization properties of the in vivo human retina. A novel phase-unwrapping method in birefringent media is described to extract the total reflectivity, accumulative retardance, and fast-axis orientation from a specially designed sequence of polarization states incident on the sample. A quarter-wave plate was employed to test the performance of the system. The average error and standard deviation of retardation measurements were 3.2° and 2.3°, respectively, and of the fast-axis orientation 1.2° and 0.7° over the range of 0°–180°. The depolarization properties of the retinal pigment epithelium were clearly observed in both retardance and fast-axis orientation image. A normalized standard deviation of the retardance and of the fast-axis orientation is introduced to segment the polarization-scrambling layer of the retinal pigment epithelium.
© 2009 Optical Society of America
OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4460) Medical optics and biotechnology : Ophthalmic optics and devices
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(260.5430) Physical optics : Polarization
ToC Category:
Medical Optics and Biotechnology
History
Original Manuscript: October 7, 2008
Manuscript Accepted: November 9, 2008
Published: January 14, 2009
Virtual Issues
Vol. 4, Iss. 3 Virtual Journal for Biomedical Optics
Citation
Mingtao Zhao and Joseph A. Izatt, "Single-camera sequential-scan-based polarization-sensitive SDOCT for retinal imaging," Opt. Lett. 34, 205-207 (2009)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-34-2-205
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