OSA's Digital Library

Optics Letters

Optics Letters


  • Editor: Alan E. Willner
  • Vol. 34, Iss. 20 — Oct. 15, 2009
  • pp: 3235–3237

Line-scanning reflectance confocal microscopy of human skin: comparison of full-pupil and divided-pupil configurations

Daniel S. Gareau, Sanjee Abeytunge, and Milind Rajadhyaksha  »View Author Affiliations

Optics Letters, Vol. 34, Issue 20, pp. 3235-3237 (2009)

View Full Text Article

Enhanced HTML    Acrobat PDF (283 KB)

Browse Journals / Lookup Meetings

Browse by Journal and Year


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools



Line-scanning, with pupil engineering and the use of linear array detectors, may enable simple, small, and low-cost confocal microscopes for clinical imaging of human epithelial tissues. However, a fundamental understanding of line-scanning performance within the highly scattering and aberrating conditions of human tissue is necessary, to translate from benchtop instrumentation to clinical implementation. The results of a preliminary investigation for reflectance imaging in skin are reported.

© 2009 Optical Society of America

OCIS Codes
(040.1240) Detectors : Arrays
(180.2520) Microscopy : Fluorescence microscopy

ToC Category:

Original Manuscript: June 8, 2009
Revised Manuscript: August 14, 2009
Manuscript Accepted: August 19, 2009
Published: October 15, 2009

Virtual Issues
Vol. 4, Iss. 12 Virtual Journal for Biomedical Optics

Daniel S. Gareau, Sanjee Abeytunge, and Milind Rajadhyaksha, "Line-scanning reflectance confocal microscopy of human skin: comparison of full-pupil and divided-pupil configurations," Opt. Lett. 34, 3235-3237 (2009)

Sort:  Author  |  Year  |  Journal  |  Reset  


  1. S.G.Gonzalez, M.Gill, and A.C.Halpern, eds., Reflectance Confocal Microscopy of Cutaneous Tumors--an Atlas with Clinical, Dermoscopic and Histological Correlations (Informa Healthcare, 2008). [PubMed]
  2. K.-B. Im, S. Han, H. Park, D. Kim, and B.-M. Kim, Opt. Express 13, 5151 (2005). [CrossRef] [PubMed]
  3. R. Wolleschensky, B. Zimmerman, and M. Kempe, J. Biomed. Opt. 11, 064011 (2006). [CrossRef]
  4. D. X. Hammer, R. D. Ferguson, T. E. Ustun, C. E. Bigelow, N. V. Iftimia, and R. H. Webb, J. Biomed. Opt. 11, 041126 (2006). [CrossRef] [PubMed]
  5. P. J. Dwyer, C. A. DiMarzio, J. M. Zavislan, W. J. Fox, and M. Rajadhyaksha, Opt. Lett. 31, 942 (2006). [CrossRef] [PubMed]
  6. P. J. Dwyer, C. A. DiMarzio, and M. Rajadhyaksha, Appl. Opt. 46, 1843 (2007). [CrossRef] [PubMed]
  7. T.Wilson, ed. Confocal Microscopy (Academic, 1990).
  8. E. H. K. Stelzer and S. Lindek, Opt. Commun. 111, 536 (1994). [CrossRef]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


Fig. 1 Fig. 2 Fig. 3

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited