Line-scanning, with pupil engineering and the use of linear array detectors, may enable simple, small, and low-cost confocal microscopes for clinical imaging of human epithelial tissues. However, a fundamental understanding of line-scanning performance within the highly scattering and aberrating conditions of human tissue is necessary, to translate from benchtop instrumentation to clinical implementation. The results of a preliminary investigation for reflectance imaging in skin are reported.
© 2009 Optical Society of America
Original Manuscript: June 8, 2009
Revised Manuscript: August 14, 2009
Manuscript Accepted: August 19, 2009
Published: October 15, 2009
Vol. 4, Iss. 12 Virtual Journal for Biomedical Optics
Daniel S. Gareau, Sanjee Abeytunge, and Milind Rajadhyaksha, "Line-scanning reflectance confocal microscopy of human skin: comparison of full-pupil and divided-pupil configurations," Opt. Lett. 34, 3235-3237 (2009)