Abstract

Phase microscopy for high-dynamic-range quantitative phase-contrast imaging of a transparent phase object was demonstrated. Using a common path Fourier domain optical coherence tomography system, this technique is capable of displacement measurement with a sensitivity of 34 pm. The limitation of 2π ambiguity restriction was overcome by the use of a phase retrieval approach performed in spectral domain. Two-dimensional quantitative phase imaging of human neonatal dermal keratinocyte cells was demonstrated to evaluate the performance of the system for cell imaging.

© 2009 Optical Society of America

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History
Original Manuscript: August 3, 2009
Manuscript Accepted: September 17, 2009
Published: October 30, 2009

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Author Affiliations

Jun Zhang, Bin Rao, Lingfeng Yu, Zhongping Chen

University of California, Irvine

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