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Optics Letters

Optics Letters


  • Editor: Alan E. Willner
  • Vol. 34, Iss. 24 — Dec. 15, 2009
  • pp: 3782–3784

Variable optical activation of human cone photoreceptors visualized using a short coherence light source

Jungtae Rha, Brett Schroeder, Pooja Godara, and Joseph Carroll  »View Author Affiliations

Optics Letters, Vol. 34, Issue 24, pp. 3782-3784 (2009)

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It has been shown that after a visible stimulus, optical oscillations of nearly all cone photoreceptors can be observed using long coherence length light and in a few cones using short coherence length light. Here, we show that after exposure to a visible stimulus, a short coherence length imaging source reveals light-evoked oscillation signals in a large number of cones. More than 80% of cones in a given retinal area are activated (modulation in the reflectance signal) after stimulation, and the pattern of their activation can be subjectively classified into one of four categories. The application of light-evoked signal detection techniques for in vivo retinal imaging may prove useful for assessing the functional status of cones in normal and diseased retinae.

© 2009 Optical Society of America

OCIS Codes
(330.0330) Vision, color, and visual optics : Vision, color, and visual optics
(330.4460) Vision, color, and visual optics : Ophthalmic optics and devices
(330.5370) Vision, color, and visual optics : Physiological optics
(330.7327) Vision, color, and visual optics : Visual optics, ophthalmic instrumentation

ToC Category:
Vision, Color, and Visual Optics

Original Manuscript: August 27, 2009
Revised Manuscript: October 20, 2009
Manuscript Accepted: October 21, 2009
Published: December 3, 2009

Virtual Issues
Vol. 5, Iss. 1 Virtual Journal for Biomedical Optics

Jungtae Rha, Brett Schroeder, Pooja Godara, and Joseph Carroll, "Variable optical activation of human cone photoreceptors visualized using a short coherence light source," Opt. Lett. 34, 3782-3784 (2009)

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