Hemodynamic measurements from individual blood cells in early mammalian embryos with Doppler swept source OCT
Optics Letters, Vol. 34, Issue 7, pp. 986-988 (2009)
http://dx.doi.org/10.1364/OL.34.000986
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Abstract
The most common and lethal birth defects affect the cardiovascular (CV) system. The mouse is a superior model for identifying and understanding mammalian CV birth defects, but there is a great need for tools that can detect early and subtle deficiencies in cardiac function in mouse embryos. We combined swept source optical coherence tomography (SS-OCT) with live mouse embryo culture protocols to generate structural two-dimensional and three-dimensional imaging and hemodynamic measurements in a live
© 2009 Optical Society of America
OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.6920) Medical optics and biotechnology : Time-resolved imaging
(280.3340) Remote sensing and sensors : Laser Doppler velocimetry
(180.1655) Microscopy : Coherence tomography
ToC Category:
Medical Optics and Biotechnology
History
Original Manuscript: November 17, 2008
Revised Manuscript: February 11, 2009
Manuscript Accepted: February 18, 2009
Published: March 20, 2009
Virtual Issues
Vol. 4, Iss. 6 Virtual Journal for Biomedical Optics
Citation
Irina V. Larina, Steven Ivers, Saba Syed, Mary E. Dickinson, and Kirill V. Larin, "Hemodynamic measurements from individual blood cells in early mammalian embryos with Doppler swept source OCT," Opt. Lett. 34, 986-988 (2009)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-34-7-986
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