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Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Editor: Alan E. Willner
  • Vol. 35, Iss. 11 — Jun. 1, 2010
  • pp: 1737–1739

Rapid spectrally encoded fluorescence imaging using a wavelength-swept source

Mathias Strupler, Etienne De Montigny, Dominic Morneau, and Caroline Boudoux  »View Author Affiliations


Optics Letters, Vol. 35, Issue 11, pp. 1737-1739 (2010)
http://dx.doi.org/10.1364/OL.35.001737


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Abstract

We present rapid imaging of fluorescent samples using spectral encoding (SE). A near-IR wavelength-swept source in used to preserve the SE of the position, despite Stokes shifts. To validate this approach, we imaged fluorescent PbS quantum dot solutions at concentrations down to 0.5 ± 0.1 μ mol / L . This simple configuration allowed acquisition rates of up to 9920 lines of 1024 pixels per second to create high-resolution images. This spectrally encoded setup could be easily miniaturized for endoscopy, thus combining high-resolution fluorescence with confocal reflectance imaging at unmatched acquisition speed.

© 2010 Optical Society of America

OCIS Codes
(170.2150) Medical optics and biotechnology : Endoscopic imaging
(170.2520) Medical optics and biotechnology : Fluorescence microscopy

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: January 27, 2010
Revised Manuscript: March 23, 2010
Manuscript Accepted: April 7, 2010
Published: May 17, 2010

Virtual Issues
Vol. 5, Iss. 10 Virtual Journal for Biomedical Optics

Citation
Mathias Strupler, Etienne De Montigny, Dominic Morneau, and Caroline Boudoux, "Rapid spectrally encoded fluorescence imaging using a wavelength-swept source," Opt. Lett. 35, 1737-1739 (2010)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-35-11-1737


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