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Optics Letters

Optics Letters


  • Editor: Alan E. Willner
  • Vol. 35, Iss. 11 — Jun. 1, 2010
  • pp: 1905–1907

Theoretical model of errors in micromirror-based three-dimensional particle tracking

Andrew J. Berglund, Matthew D. McMahon, Jabez J. McClelland, and J. Alexander Liddle  »View Author Affiliations

Optics Letters, Vol. 35, Issue 11, pp. 1905-1907 (2010)

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Several recently developed particle-tracking and imaging methods have achieved three-dimensional sensitivity through the introduction of angled micromirrors into the observation volume of an optical microscope. We model the imaging response of such devices and show how the direct and reflected images of a fluorescent particle are affected. In particle-tracking applications, asymmetric image degradation manifests itself as systematic tracking errors. Based on our results, we identify strategies for reducing systematic errors to the 10 nm level in practical applications.

OCIS Codes
(180.6900) Microscopy : Three-dimensional microscopy
(220.2740) Optical design and fabrication : Geometric optical design
(350.3950) Other areas of optics : Micro-optics

ToC Category:

Original Manuscript: December 4, 2009
Revised Manuscript: March 8, 2010
Manuscript Accepted: March 29, 2010
Published: May 28, 2010

Virtual Issues
Vol. 5, Iss. 10 Virtual Journal for Biomedical Optics

Andrew J. Berglund, Matthew D. McMahon, Jabez J. McClelland, and J. Alexander Liddle, "Theoretical model of errors in micromirror-based three-dimensional particle tracking," Opt. Lett. 35, 1905-1907 (2010)

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