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Optics Letters

Optics Letters


  • Editor: Alan E. Willner
  • Vol. 35, Iss. 2 — Jan. 15, 2010
  • pp: 181–183

Two-photon microscopy by wavelength-swept pulses delivered through single-mode fiber

Jeon Woong Kang, Pilhan Kim, Carlo Amadeo Alonzo, Hyunsung Park, and Seok H. Yun  »View Author Affiliations

Optics Letters, Vol. 35, Issue 2, pp. 181-183 (2010)

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Nonlinear microscopy through flexible fiber-optic catheters has potential in clinical diagnostic applications. Here, we demonstrate a new approach based on wavelength-swept narrowband pulses that permits simple fiber-optic delivery without need of the dispersion management and allows nonmechanical beam scanning. Using 0.86 ps pulses rapidly tuned from 789 nm to 822 nm at a sweep rate of 200 Hz , we demonstrate two-photon fluorescence and second-harmonic generation imaging through a 5 - m -long standard single-mode fiber.

© 2010 Optical Society of America

OCIS Codes
(110.0180) Imaging systems : Microscopy
(140.3600) Lasers and laser optics : Lasers, tunable
(180.4315) Microscopy : Nonlinear microscopy

ToC Category:
Imaging Systems

Original Manuscript: September 16, 2009
Revised Manuscript: November 30, 2009
Manuscript Accepted: December 3, 2009
Published: January 13, 2010

Virtual Issues
Vol. 5, Iss. 3 Virtual Journal for Biomedical Optics

Jeon Woong Kang, Pilhan Kim, Carlo Amadeo Alonzo, Hyunsung Park, and Seok H. Yun, "Two-photon microscopy by wavelength-swept pulses delivered through single-mode fiber," Opt. Lett. 35, 181-183 (2010)

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