OSA's Digital Library

Optics Letters

Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Editor: Alan E. Willner
  • Vol. 35, Iss. 21 — Nov. 1, 2010
  • pp: 3673–3675

Single-strand DNA detection using a planar photonic-crystal-waveguide-based sensor

V. Toccafondo, J. García-Rupérez, M. J. Bañuls, A. Griol, J. G. Castelló, S. Peransi-Llopis, and A. Maquieira  »View Author Affiliations


Optics Letters, Vol. 35, Issue 21, pp. 3673-3675 (2010)
http://dx.doi.org/10.1364/OL.35.003673


View Full Text Article

Enhanced HTML    Acrobat PDF (431 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

We report an experimental demonstration of single-strand DNA (ssDNA) detection at room temperature using a photonic-crystal-waveguide-based optical sensor. The sensor surface was previously biofunctionalized with ssDNA probes to be used as specific target receptors. Our experiments showed that it is possible to detect these hybridization events using planar photonic-crystal structures, reaching an estimated detection limit as low as 19.8 nM for the detection of the complementary DNA strand.

© 2010 Optical Society of America

OCIS Codes
(130.6010) Integrated optics : Sensors
(130.5296) Integrated optics : Photonic crystal waveguides

ToC Category:
Integrated Optics

History
Original Manuscript: July 30, 2010
Revised Manuscript: September 14, 2010
Manuscript Accepted: September 29, 2010
Published: October 28, 2010

Virtual Issues
Vol. 6, Iss. 1 Virtual Journal for Biomedical Optics

Citation
V. Toccafondo, J. García-Rupérez, M. J. Bañuls, A. Griol, J. G. Castelló, S. Peransi-Llopis, and A. Maquieira, "Single-strand DNA detection using a planar photonic-crystal-waveguide-based sensor," Opt. Lett. 35, 3673-3675 (2010)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-35-21-3673

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited