Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Utility of biodegradable plasmonic nanoclusters in photoacoustic imaging

Not Accessible

Your library or personal account may give you access

Abstract

Plasmonic metal nanoparticles are used in photoacoustic imaging as contrast agents because of their resonant optical absorption properties in the visible and near-IR regions. However, the nanoparticles could accumulate and result in long-term toxicity in vivo, because they are generally not biodegradable. Recently, biodegradable plasmonic gold nanoclusters, consisting of sub-5nm primary gold nanoparticles and biodegradable polymer stabilizer, were introduced. In this Letter, we demonstrate the feasibility of biodegradable nanoclusters as a photoacoustic contrast agent. We performed photoacoustic and ultrasound imaging of a tissue-mimicking phantom with inclusions containing nanoclusters at various concentrations. The results indicate that the biodegradable gold nanoclusters can be used as effective contrast agents in photoacoustic imaging.

© 2010 Optical Society of America

Full Article  |  PDF Article
More Like This
Thermal stability of biodegradable plasmonic nanoclusters in photoacoustic imaging

Soon Joon Yoon, Avinash Murthy, Keith P. Johnston, Konstantin V. Sokolov, and Stanislav Y. Emelianov
Opt. Express 20(28) 29479-29487 (2012)

Nonlinear photoacoustic signal increase from endocytosis of gold nanoparticles

Seung Yun Nam, Laura M. Ricles, Laura J. Suggs, and Stanislav Y. Emelianov
Opt. Lett. 37(22) 4708-4710 (2012)

Prospects of molecular photoacoustic imaging at 1064 nm wavelength

Kimberly Homan, Seungsoo Kim, Yun-Sheng Chen, Bo Wang, Srivalleesha Mallidi, and Stanislav Emelianov
Opt. Lett. 35(15) 2663-2665 (2010)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (4)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved