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Multiwaveguide implantable probe for light delivery to sets of distributed brain targets |
Optics Letters, Vol. 35, Issue 24, pp. 4133-4135 (2010)
http://dx.doi.org/10.1364/OL.35.004133
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Abstract
Optical fibers are commonly inserted into living tissues such as the brain in order to deliver light to deep targets for neuroscientific and neuroengineering applications such as optogenetics, in which light is used to activate or silence neurons expressing specific photosensitive proteins. However, an optical fiber is limited to delivering light to a single target within the three-dimensional structure of the brain. We here demonstrate a multiwaveguide probe capable of independently delivering light to multiple targets along the probe axis, thus enabling versatile optical control of sets of distributed brain targets. The 1.45-cm-long probe is microfabricated in the form of a 360-μm-wide array of 12 parallel silicon oxynitride (SiON) multimode waveguides clad with
© 2010 Optical Society of America
OCIS Codes
(130.3120) Integrated optics : Integrated optics devices
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(230.3990) Optical devices : Micro-optical devices
(230.7370) Optical devices : Waveguides
(130.2755) Integrated optics : Glass waveguides
(130.3990) Integrated optics : Micro-optical devices
ToC Category:
Integrated Optics
History
Original Manuscript: September 9, 2010
Manuscript Accepted: October 20, 2010
Published: December 8, 2010
Citation
Anthony N. Zorzos, Edward S. Boyden, and Clifton G. Fonstad, "Multiwaveguide implantable probe for light delivery to sets of distributed brain targets," Opt. Lett. 35, 4133-4135 (2010)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-35-24-4133
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