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Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Editor: Alan E. Willner
  • Vol. 35, Iss. 9 — May. 1, 2010
  • pp: 1467–1469

Depth-resolved imaging of capillary networks in retina and choroid using ultrahigh sensitive optical microangiography

Ruikang K. Wang, Lin An, Peter Francis, and David J. Wilson  »View Author Affiliations


Optics Letters, Vol. 35, Issue 9, pp. 1467-1469 (2010)
http://dx.doi.org/10.1364/OL.35.001467


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Abstract

We demonstrate the depth-resolved and detailed ocular perfusion maps within retina and choroid can be obtained from an ultrahigh sensitive optical microangiography (OMAG). As opposed to the conventional OMAG, we apply the OMAG algorithm along the slow scanning axis to achieve the ultrahigh sensitive imaging to the slow flows within capillaries. We use an 840 nm system operating at an imaging rate of 400   frames s that requires 3 s to complete one 3D scan of 3 × 3 mm 2 area on retina. We show the superior imaging performance of OMAG to provide functional images of capillary level microcirculation at different land-marked depths within retina and choroid that correlate well with the standard retinal pathology.

© 2010 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4460) Medical optics and biotechnology : Ophthalmic optics and devices

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: January 13, 2010
Revised Manuscript: March 31, 2010
Manuscript Accepted: April 2, 2010
Published: April 30, 2010

Virtual Issues
Vol. 5, Iss. 9 Virtual Journal for Biomedical Optics

Citation
Ruikang K. Wang, Lin An, Peter Francis, and David J. Wilson, "Depth-resolved imaging of capillary networks in retina and choroid using ultrahigh sensitive optical microangiography," Opt. Lett. 35, 1467-1469 (2010)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-35-9-1467


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References

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