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  • Vol. 36, Iss. 15 — Aug. 1, 2011
  • pp: 2791–2793

Method to quantitate absorption coefficients from single fiber reflectance spectra without knowledge of the scattering properties

Stephen C. Kanick, Dominic J. Robinson, Henricus J. C. M. Sterenborg, and Arjen Amelink  »View Author Affiliations


Optics Letters, Vol. 36, Issue 15, pp. 2791-2793 (2011)
http://dx.doi.org/10.1364/OL.36.002791


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Abstract

This study presents a methodology to accurately extract the absorption coefficient from single fiber reflectance spectra measured in turbid media without a priori knowledge of either the reduced scattering coefficient or the phase function. This novel approach accounts for the interrelated effects these properties have on the photon path length, yielding estimates of an absorption coefficient on average within < 7.5 % of true values over a wide range of biologically relevant optical properties.

© 2011 Optical Society of America

OCIS Codes
(170.1470) Medical optics and biotechnology : Blood or tissue constituent monitoring
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(290.1350) Scattering : Backscattering
(290.5820) Scattering : Scattering measurements
(290.7050) Scattering : Turbid media

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: May 13, 2011
Revised Manuscript: June 8, 2011
Manuscript Accepted: June 15, 2011
Published: July 20, 2011

Virtual Issues
Vol. 6, Iss. 9 Virtual Journal for Biomedical Optics

Citation
Stephen C. Kanick, Dominic J. Robinson, Henricus J. C. M. Sterenborg, and Arjen Amelink, "Method to quantitate absorption coefficients from single fiber reflectance spectra without knowledge of the scattering properties," Opt. Lett. 36, 2791-2793 (2011)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-36-15-2791


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References

  1. S. C. Kanick, C. van der Leest, J. G. J. V. Aerts, H. C. Hoogsteden, S. Kaščáková, H. J. C. M. Sterenborg, and A. Amelink, J. Biomed. Opt. 15, 017004 (2010). [CrossRef] [PubMed]
  2. S. C. Kanick, D. J. Robinson, H. J. C. M. Sterenborg, and A. Amelink, Phys. Med. Biol. 54, 6991 (2009). [CrossRef] [PubMed]
  3. F. Bevilacqua and C. Depeursinge, J. Opt. Soc. Am. A 16, 2935 (1999). [CrossRef]
  4. J. R. Mourant, J. Boyer, A. H. Hielscher, and I. J. Bigio, Opt. Lett. 21, 546 (1996). [CrossRef] [PubMed]
  5. S. C. Kanick, U. A. Gamm, M. Schouten, H. J. C. M. Sterenborg, D. J. Robinson, and A. Amelink, Biomed. Opt. Express 2, 1687 (2011). [CrossRef] [PubMed]
  6. P. R. Bargo, S. A. Prahl, and S. L. Jacques, Appl. Opt. 42, 3187 (2003). [CrossRef] [PubMed]
  7. A. Amelink, D. J. Robinson, and H. J. C. M. Sterenborg, J. Biomed. Opt. 13, 054044 (2008). [CrossRef] [PubMed]

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