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Optics Letters

Optics Letters

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  • Vol. 36, Iss. 2 — Jan. 15, 2011
  • pp: 139–141

Fast voice-coil scanning optical-resolution photoacoustic microscopy

Lidai Wang, Konstantin Maslov, Junjie Yao, Bin Rao, and Lihong V. Wang  »View Author Affiliations


Optics Letters, Vol. 36, Issue 2, pp. 139-141 (2011)
http://dx.doi.org/10.1364/OL.36.000139


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Abstract

We developed a photoacoustic imaging system that has real-time imaging capability with optical resolution. The imaging system is capable of scanning at 20 Hz over a 9 mm range and up to 40 Hz over a 1 mm scanning range. A focused laser beam provides a lateral resolution of 3.4 μm as measured in an optically nonscattering medium. Flows of micrometer-sized carbon particles or whole blood in a silicone tube and individual red blood cells (RBCs) in mouse ear capillaries were also imaged in real time, demonstrating the capability to image highly dynamic processes in vivo at a micrometer-scale resolution.

© 2011 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5120) Medical optics and biotechnology : Photoacoustic imaging
(180.5810) Microscopy : Scanning microscopy

ToC Category:
Imaging Systems

History
Original Manuscript: September 22, 2010
Revised Manuscript: November 24, 2010
Manuscript Accepted: November 27, 2010
Published: January 6, 2011

Virtual Issues
Vol. 6, Iss. 2 Virtual Journal for Biomedical Optics

Citation
Lidai Wang, Konstantin Maslov, Junjie Yao, Bin Rao, and Lihong V. Wang, "Fast voice-coil scanning optical-resolution photoacoustic microscopy," Opt. Lett. 36, 139-141 (2011)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-36-2-139

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» Media 1: AVI (4155 KB)     

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