Light-assisted ionization accompanying coherent anti-Stokes Raman scattering (CARS) of ultrashort laser pulses in brain tissue is shown to manifest itself in a detectable blueshift of the anti-Stokes signal. This blueshift can serve as an indicator of ionization processes in CARS-based neuroimaging.
© 2011 Optical Society of America
Original Manuscript: August 24, 2010
Revised Manuscript: December 5, 2010
Manuscript Accepted: December 20, 2010
Published: February 8, 2011
Vol. 6, Iss. 3 Virtual Journal for Biomedical Optics
Aleksandr A. Voronin, Ilya V. Fedotov, Lyubov V. Doronina-Amitonova, Olga I. Ivashkina, Marina A. Zots, Andrei B. Fedotov, Konstantin V. Anokhin, and Aleksei M. Zheltikov, "Ionization penalty in nonlinear Raman neuroimaging," Opt. Lett. 36, 508-510 (2011)