Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Real-time four-dimensional optical-resolution photoacoustic microscopy with Au nanoparticle-assisted subdiffraction-limit resolution

Not Accessible

Your library or personal account may give you access

Abstract

Photoacoustic microscopy (PAM) offers label-free, optical absorption contrast. A high-speed, high-resolution PAM system in an inverted microscope configuration with a laser pulse repetition rate of 100,000Hz and a stationary ultrasonic transducer was built. Four-dimensional in vivo imaging of microcirculation in mouse skin was achieved at 18 three-dimensional volumes per second with repeated two-dimensional (2D) raster scans of 100 by 50 points. The corresponding 2D B-scan (50 A-lines) frame rate was 1800Hz, and the one-dimensional A-scan rate was 90,000Hz. The lateral resolution is 0.23±0.03μm for Au nanowire imaging, which is 2.0 times below the diffraction limit.

© 2011 Optical Society of America

Full Article  |  PDF Article
More Like This
Real-time handheld optical-resolution photoacoustic microscopy

Parsin Hajireza, Wei Shi, and Roger J. Zemp
Opt. Express 19(21) 20097-20102 (2011)

Laser-scanning optical-resolution photoacoustic microscopy

Zhixing Xie, Shuliang Jiao, Hao F. Zhang, and Carmen A. Puliafito
Opt. Lett. 34(12) 1771-1773 (2009)

Wide-field two-dimensional multifocal optical-resolution photoacoustic-computed microscopy

Jun Xia, Guo Li, Lidai Wang, Mohammadreza Nasiriavanaki, Konstantin Maslov, John A. Engelbach, Joel R. Garbow, and Lihong V. Wang
Opt. Lett. 38(24) 5236-5239 (2013)

Supplementary Material (1)

Media 1: AVI (281 KB)     

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (5)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved