A phase-contrast volume holographic imaging system for three-dimensional contrast enhancement is presented. The system utilizes a spatial filter placed on a conjugate plane to the volume holographic pupil to simultaneously enhance weak phase information at different depths within an object. The proposed system was validated with experimental image data obtained in mouse colon samples and quantitative measurements of modulation transfer function as well.
© 2011 Optical Society of America
Original Manuscript: December 13, 2010
Revised Manuscript: February 17, 2011
Manuscript Accepted: February 18, 2011
Published: March 31, 2011
Vol. 6, Iss. 5 Virtual Journal for Biomedical Optics
Yuan Luo, Erich de Leon, Jose Castro, Justin Lee, Jennifer K. Barton, Raymond K. Kostuk, and George Barbastathis, "Phase-contrast volume holographic imaging system," Opt. Lett. 36, 1290-1292 (2011)