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Molecular layer detection on a diffractive optical balance |
Optics Letters, Vol. 37, Issue 19, pp. 4098-4100 (2012)
http://dx.doi.org/10.1364/OL.37.004098
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Abstract
Diffraction-based molecular detection is achieved by etching optical gratings into thermal oxide on silicon. The gratings perform as a stable common-path diffractive optical balance (DOB) designed to operate near a missing diffraction order. The biosensor is operated in an off-null condition with a phase bias to produce a high-contrast responsivity that is linear in accumulated molecules but with a low background. The DOB linear responsivity is a factor of 20 larger than the reflectometric responsivity of planar thermal oxide.
© 2012 Optical Society of America
OCIS Codes
(240.0310) Optics at surfaces : Thin films
(280.1415) Remote sensing and sensors : Biological sensing and sensors
(240.3990) Optics at surfaces : Micro-optical devices
ToC Category:
Optics at Surfaces
History
Original Manuscript: July 13, 2012
Revised Manuscript: August 29, 2012
Manuscript Accepted: August 29, 2012
Published: September 26, 2012
Citation
Xuefeng Wang, Ming Zhao, and David D. Nolte, "Molecular layer detection on a diffractive optical balance," Opt. Lett. 37, 4098-4100 (2012)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-37-19-4098
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