OSA's Digital Library

Optics Letters

Optics Letters


  • Editor: Alan E. Willner
  • Vol. 37, Iss. 24 — Dec. 15, 2012
  • pp: 5115–5117

Optofluidic jet waveguide for laser-induced fluorescence spectroscopy

Gianluca Persichetti, Genni Testa, and Romeo Bernini  »View Author Affiliations

Optics Letters, Vol. 37, Issue 24, pp. 5115-5117 (2012)

View Full Text Article

Enhanced HTML    Acrobat PDF (378 KB)

Browse Journals / Lookup Meetings

Browse by Journal and Year


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools



An optofluidic water-jet waveguide on chip for fluorescence analysis is presented. A high-speed water stream produced by means of a microchannel acts at the same time as the solution to analyze and as the collecting optical waveguide. The absence of solid walls and the very optically smooth surface of the liquid stream permits a strong increase of the signal-to-noise ratio. The device layout allows a self-alignment direct coupling of a water-jet waveguide with a multimode optical fiber connected to the detector. The performances of the integrated system are tested on Cy5 water solutions. For a 4.5 mm long water-jet waveguide, the measured limit of detection (LOD) is 2.56 nM and filter-free detection is possible with an LOD of 6.11 nM.

© 2012 Optical Society of America

OCIS Codes
(130.6010) Integrated optics : Sensors
(230.7370) Optical devices : Waveguides

ToC Category:
Integrated Optics

Original Manuscript: October 2, 2012
Revised Manuscript: November 9, 2012
Manuscript Accepted: November 13, 2012
Published: December 7, 2012

Virtual Issues
Vol. 8, Iss. 1 Virtual Journal for Biomedical Optics

Gianluca Persichetti, Genni Testa, and Romeo Bernini, "Optofluidic jet waveguide for laser-induced fluorescence spectroscopy," Opt. Lett. 37, 5115-5117 (2012)

Sort:  Author  |  Year  |  Journal  |  Reset  


  1. P. Hua, J. P. Hole, J. S. Wilkinson, G. Proll, J. Tschmealk, G. Gauglitz, M. A. Jackson, R. Nudd, H. M. T. Griffith, R. A. Abuknesha, J. Kasier, and P. Kraemmer, Opt. Express 13, 1124 (2005). [CrossRef]
  2. C. R. Taitt, G. P. Anderson, and F. S. Ligler, Biosens. Bioelectron. 20, 2470 (2005). [CrossRef]
  3. X. Fan and I. M. White, Nat. Photonics 5, 591 (2011). [CrossRef]
  4. R. Bernini, N. Cennamo, A. Minardo, and L. Zeni, IEEE Sens. J. 6, 1218 (2006). [CrossRef]
  5. R. Irawan, C. M. Tay, S. C. Tjin, and C. Y. Fu, Lab Chip 6, 1095 (2006). [CrossRef]
  6. R. Gravina, G. Testa, and R. Bernini, Sensors 9, 10423 (2009). [CrossRef]
  7. A. Chen, M. M. Eberle, E. J. Lunt, S. Liu, K. Leake, M. I. Rudenko, A. R. Hawkins, and H. Schmidt, Lab Chip 11, 1502 (2011). [CrossRef]
  8. S. Smolka, M. Barth, and O. Benson, Opt. Express 15, 12783 (2007). [CrossRef]
  9. W. P. Risk, H.-C. Kim, R. D. Miller, H. Temkin, and S. Gangopadhyay, Opt. Express 12, 6446 (2004). [CrossRef]
  10. Y. Zhao, M. Jenkins, P. Measor, K. Leake, S. Liu, H. Schmidt, and A. R. Hawkins, Appl. Phys. Lett. 98, 091104 (2011). [CrossRef]
  11. D. Colladon, Compt. Rend. 15, 800 (1842).
  12. B. Richerzhagen, Solid State Technol. 44, 25 (2001).
  13. S. Folestad, L. Johnson, B. Josefsson, and B. Galle, Anal. Chem. 54, 925 (1982). [CrossRef]
  14. S. J. Mackenzie, J. Hodgkinson, M. Johnson, and J. P. Dakin, “A falling analyte stream configuration for spectroscopic analysis of aqueous solutions,” presented at Europto EnviroSense, Munich, Germany (16–20 June 1997).
  15. J. Inczedy, T. Lengyel, and A. M. Ure, Compendium of Analytical Nomenclature. The Orange Book, 3rd ed. (Blackwell, 1998).

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited