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Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Editor: Alan E. Willner
  • Vol. 37, Iss. 5 — Mar. 1, 2012
  • pp: 872–874

Dual-modality photothermal optical coherence tomography and magnetic-resonance imaging of carbon nanotubes

Jason M. Tucker-Schwartz, Tu Hong, Daniel C. Colvin, Yaqiong Xu, and Melissa C. Skala  »View Author Affiliations


Optics Letters, Vol. 37, Issue 5, pp. 872-874 (2012)
http://dx.doi.org/10.1364/OL.37.000872


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Abstract

We demonstrate polyethylene-glycol-coated single-walled carbon nanotubes (CNTs) as contrast agents for both photothermal optical coherence tomography (OCT) and magnetic-resonance imaging (MRI). Photothermal OCT was accomplished with a spectral domain OCT system with an amplitude-modulated 750 nm pump beam using 10 mW of power, and T2 MRI was achieved with a 4.7 T animal system. Photothermal OCT and T2 MRI achieved sensitivities of nanomolar concentrations to CNTs dispersed in amine-terminated polyethylene glycol, thus establishing the potential for dual-modality molecular imaging with CNTs.

© 2012 Optical Society of America

OCIS Codes
(110.4190) Imaging systems : Multiple imaging
(110.4500) Imaging systems : Optical coherence tomography
(160.4236) Materials : Nanomaterials

ToC Category:
Imaging Systems

History
Original Manuscript: December 12, 2011
Revised Manuscript: January 19, 2012
Manuscript Accepted: January 19, 2012
Published: February 24, 2012

Virtual Issues
Vol. 7, Iss. 5 Virtual Journal for Biomedical Optics

Citation
Jason M. Tucker-Schwartz, Tu Hong, Daniel C. Colvin, Yaqiong Xu, and Melissa C. Skala, "Dual-modality photothermal optical coherence tomography and magnetic-resonance imaging of carbon nanotubes," Opt. Lett. 37, 872-874 (2012)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-37-5-872


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