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Optics Letters


  • Editor: Alan E. Willner
  • Vol. 38, Iss. 15 — Aug. 1, 2013
  • pp: 2683–2686

Random-access optical-resolution photoacoustic microscopy using a digital micromirror device

Jinyang Liang, Yong Zhou, Amy W. Winkler, Lidai Wang, Konstantin I. Maslov, Chiye Li, and Lihong V. Wang  »View Author Affiliations

Optics Letters, Vol. 38, Issue 15, pp. 2683-2686 (2013)

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We developed random-access optical-resolution photoacoustic microscopy using a digital micromirror device. This system can rapidly scan arbitrarily shaped regions of interest within a 40μm×40μm imaging area with a lateral resolution of 3.6 μm. To identify a region of interest, a global structural image is first acquired, then the selected region is scanned. The random-access ability was demonstrated by imaging two static samples, a carbon fiber cross and a monolayer of red blood cells, with an acquisition rate up to 4 kHz. The system was then used to monitor blood flow in vivo in real time within user-selected capillaries in a mouse ear. By imaging only the capillary of interest, the frame rate was increased by up to 9.2 times.

© 2013 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5120) Medical optics and biotechnology : Photoacoustic imaging
(180.5810) Microscopy : Scanning microscopy

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: May 6, 2013
Revised Manuscript: June 25, 2013
Manuscript Accepted: June 27, 2013
Published: July 22, 2013

Virtual Issues
Vol. 8, Iss. 9 Virtual Journal for Biomedical Optics

Jinyang Liang, Yong Zhou, Amy W. Winkler, Lidai Wang, Konstantin I. Maslov, Chiye Li, and Lihong V. Wang, "Random-access optical-resolution photoacoustic microscopy using a digital micromirror device," Opt. Lett. 38, 2683-2686 (2013)

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